Olopatadine hydrochloride

描述

Chemical Properties‌: Olopatadine hydrochloride (CAS: 140462-76-6) is a white to off-white crystalline powder with a molecular formula of C21H24ClNO3 and a melting point of 242–245°C, exhibiting high purity (≥98% HPLC) for pharmaceutical use‌。
Dual Mechanism‌: It acts as a selective H1 receptor antagonist and mast cell stabilizer, effectively inhibiting histamine release and reducing allergic responses without significant CNS or cardiac side effects‌。
‌Applications‌: Primarily used in ophthalmic solutions (0.1%) for allergic conjunctivitis and nasal sprays (0.6%) for seasonal rhinitis, with broad clinical efficacy and safety‌。